Follow-up of pregnant women with active cytomegalovirus infection

Pregnant women [60]with and without serological evidence of active cytomegalovirus [CMV]infection were followed until delivery to detect the incidence and types of overt congenital CMV infection in neonates in Mosul, Iraq. Infection was diagnosed by the detection of CMV-IgM, using ELISA. CMV-IgM was...

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Bibliographic Details
Published inEastern Mediterranean health journal Vol. 5; no. 5; pp. 1049 - 1054
Main Authors Al Ali, H. Y., Yasseen, S. A., Raof, T. Y.
Format Journal Article
LanguageEnglish
Published 15.10.1999
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Summary:Pregnant women [60]with and without serological evidence of active cytomegalovirus [CMV]infection were followed until delivery to detect the incidence and types of overt congenital CMV infection in neonates in Mosul, Iraq. Infection was diagnosed by the detection of CMV-IgM, using ELISA. CMV-IgM was detected in cord blood samples of six [10%]overtly sick infants [with different congenital malformations]born to mothers with active CMV infection. Central nervous system abnormalities were detected in all six cases [two with microcephaly and four with hydrocephaly]. Congenital CMV infection should be suspected in infants born with congenital malformations, especially those of the central nervous system. The detection of a significant number of hydrocephalus cases in our study is notable
ISSN:1020-3397
1687-1634
DOI:10.26719/1999.5.5.949