Triterpene constituents from the fruits of Cyclocarya paliurus and their anti-HIV-1 IIIB activity

Four new norceanothane-type triterpenes, cyclopalin ( ), and sixteen known compounds ( ) were obtained from the fruits of . Their structures were determined by spectroscopic data, experimental electronic circular dichroism (ECD) and X-ray single crystal analyses. All isolated compounds were assayed...

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Published inNatural product research Vol. 37; no. 11; pp. 1787 - 1796
Main Authors Tu, Wen-Chao, Luo, Rong-Hua, Yuan, En, Sakah, Kaunda-Joseph, Yang, Quan-Yu, Xiao, Wei-Lie, Zheng, Yong-Tang, Liu, Mei-Feng
Format Journal Article
LanguageEnglish
Published England 03.06.2023
Subjects
Fruit
Juglandaceae - chemistry
Plant Leaves - chemistry
Spectrum Analysis
Triterpenes - chemistry
Juglandaceae
norceanothane-type triterpenes
Cyclocarya paliurus
anti-HIV-1IIIB activity
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Summary:Four new norceanothane-type triterpenes, cyclopalin ( ), and sixteen known compounds ( ) were obtained from the fruits of . Their structures were determined by spectroscopic data, experimental electronic circular dichroism (ECD) and X-ray single crystal analyses. All isolated compounds were assayed for their anti-HIV-1 activity. Compound exhibited potent anti-HIV-1 activity with an EC value of 1.32 μM (SI = 151.52).
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2022.2120874