Investigation of the Effects of Boron Addition to Drinking Water of Rats on Hematologic Parameters and Serum Boron, Calcium, Phosphorus and Magnesium Levels

• Published in: Balıkesir Sağlık Bilimleri Dergisi Vol. 14; no. 1; p. 24
• Main Authors: Susar, Hasan, Çelebi, Çağla, Çelebi, Murat, Rüstemoğlu, Okan, Dinç, Pelin, Karahan, İzzet
• Format: Journal Article
• Language: English
• Published: Balıkesir Balikesir University, Faculty of Engineering Department of Industrial Engineering 28.03.2025
• Subjects: Albinism; Boron; Drinking water; Phosphorus
• ISSN: 2146-9601; 2147-2238
• DOI: 10.53424/balikesirsbd.1602074

Objective: In this study, it was aimed to determine the effect of boron added to the drinking water of rats on serum boron levels, calcium, magnesium and phosphorus concentrations and the changes that may occur in hematological parameters. Materials and Methods: A total of 12 250-350 g Wistar Albino male rats, 6 in the control group and 6 in the experimental group, were used in the study. The rats were fed ad libitum and 2 mg/day/rat/25 ml borax decahydrate (Sigma) was added to the drinking water. At the end of 14 days, the rats were decapitated. Serum boron analysis by ICP-OES was performed according to Tokay and Bagdat (2022). In addition; Ca, Mg, P concentrations were determined with a biochemical analyzer device. Results: When the serum boron levels of the rats were analysed, those in the experimental group were significantly higher (p:0.0107) than those in the control group. However, there was no effect on haematological parameters or serum calcium, magnesium and phosphorus levels. Conclusion: As a result of this study, it was determined that boron given to rats with drinking water had no effect on the minerals examined. However, it was concluded that more information could be obtained with more comprehensive studies on this subject.