Tn 6060 , a Transposon from a Genomic Island in a Pseudomonas aeruginosa Clinical Isolate That Includes Two Class 1 Integrons

A 25,441-bp transposon was recovered from a Pseudomonas aeruginosa clinical isolate. While the transposition module was >99% identical to sequence of Tn 1403 , the element had been subject to rearrangements, with two In70.2-like class 1 integrons inserted into it in an unusual “tail-to-tail” conf...

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Published inAntimicrobial agents and chemotherapy Vol. 53; no. 12; pp. 5294 - 5296
Main Authors Chowdhury, Piklu Roy, Merlino, John, Labbate, Maurizio, Cheong, Elaine Y.-L., Gottlieb, Thomas, Stokes, H. W.
Format Journal Article
LanguageEnglish
Published 01.12.2009
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ISSN0066-4804
1098-6596
DOI10.1128/AAC.00687-09

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Summary:A 25,441-bp transposon was recovered from a Pseudomonas aeruginosa clinical isolate. While the transposition module was >99% identical to sequence of Tn 1403 , the element had been subject to rearrangements, with two In70.2-like class 1 integrons inserted into it in an unusual “tail-to-tail” configuration. One cassette array was the same as that in In70.2; however, the second was different, generating a transposon that collectively includes six resistance cassettes.
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00687-09