ChemInform Abstract: Improved Access to Huprine Derivatives Functionalized at Position 9

The synthetic route towards huprine derivatives (I) with different functional groups at the C9‐position consists of three main steps: enol formation from a bicyclic ketone, Suzuki—Miyaura cross coupling with different boranes and a Friedlaender condensation to access the quinoline moiety.

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Bibliographic Details
Published inChemInform Vol. 47; no. 28; p. no
Main Authors Oukoloff, Killian, Chao, Sovy, Cieslikiewicz‐Bouet, Monika, Mougeot, Romain, Jean, Ludovic, Renard, Pierre‐Yves
Format Journal Article
LanguageEnglish
Published Weinheim WILEY‐VCH Verlag 01.06.2016
Wiley Subscription Services, Inc
Subjects
fused pyridine derivatives
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Summary:The synthetic route towards huprine derivatives (I) with different functional groups at the C9‐position consists of three main steps: enol formation from a bicyclic ketone, Suzuki—Miyaura cross coupling with different boranes and a Friedlaender condensation to access the quinoline moiety.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201628201