Long COVID Syndrome: Clinical Presentation, Pathophysiology, Management

• Published in: 계명의대학술지, 42(2) pp. 71 - 74
• Main Authors: Cho Yoon Jeong, 김대현
• Format: Journal Article
• Language: English
• Published: 계명대학교 의과대학 15.12.2023
• Subjects: 의학일반
• ISSN: 2092-8335; 2733-5380
• DOI: 10.46308/kmj.2023.00269

Long coronavirus disease (COVID) syndrome is persistent symptoms and complications that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 infections. Symptoms associated with long COVID can vary widely from person to person but commonly include: fatigue, shortness of breath, chest pain or discomfort, joint pain, difficulty concentrating (brain fog), headache, loss of taste or smell, sleep disturbances, palpitations, persistent cough. Possible pathophysiologic theories are viral persistence, dysregulated immune response, autoimmune response, endothelial dysfunction, gut dysbiosis, damage to organs and tissues, neurological involvement, post-viral syndrome. Although current diagnostic and treatment options are insufficient, the management aim to alleviate symptoms, improve quality of life, and support recovery. The possible therapies and interventions that may be considered are symptomatic management, rehabilitation and exercise, respiratory support, cognitive and psychological support, sleep management, nutritional support, support groups and patient education, anti-inflammatory drugs, immuno-modulatory therapies. For patients enduring prolonged suffering from this long COVID syndrome, a multidisciplinary approach is essential for comprehensive management. KCI Citation Count: 0