397A Meta-Analysis of Randomized Clinical Trials on Calcium Intake for Obesity Indices
Abstract Background There was no consistent finding of changes of obesity indices including fat mass by calcium supplements and dairy products intervention. Therefore, we conducted the meta-analysis of evidence on calcium supplements and dairy products (≥ 12 weeks) on changes in the obesity index (f...
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Published in | International journal of epidemiology Vol. 50; no. Supplement_1 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
01.09.2021
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Online Access | Get full text |
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Summary: | Abstract
Background
There was no consistent finding of changes of obesity indices including fat mass by calcium supplements and dairy products intervention. Therefore, we conducted the meta-analysis of evidence on calcium supplements and dairy products (≥ 12 weeks) on changes in the obesity index (fat mass, as well as weight, body mass index, waist circumference) from randomized controlled trials (RCTs).
Methods
We searched for original articles during the last 10 years until August 19, 2019, using PubMed and EMBASE. The extracted data were analysed with random effects, inverse variance model using Review Manager 5.3 ver.
Results
Finally, ten RCTs with calcium supplements and fourteen RCTs with dairy products among adults aged 18 years old or over were selected. The intervention with calcium supplements showed significant change of fat mass (SMD, 95% CI; -0.21 [-0.37, -0.04], p = 0.02), but not in changes in body weight (p = 0.45), BMI (p = 0.14) and WC (p = 0.88). Dairy products also showed significant results in changes of fat mass (SMD, 95% CI; -0.51 [-0.90, -0.11], p = 0.01) as well as BMI (WMD, 95% CI; -0.46 [-0.67, -0.26], p < 0.00001), but not in changes of body weight (p = 0.70) and WC (p = 0.27).
Conclusions
The fat mass may be reduced by both calcium supplements and dairy products intervention over 12 weeks among adults 18 years old or over. Dairy products may be beneficial for BMI reduction.
Key messages
Dietary calcium intake might reduce fat mass in adults (≥ 18 years). |
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ISSN: | 0300-5771 1464-3685 |
DOI: | 10.1093/ije/dyab168.283 |