Synthesis of Core-Shell Nanoparticles (Cu:Se) by Plasma Jet for Parasitic Leishmaniasis Treatment

• Published in: Plasma medicine Vol. 13; no. 4; pp. 21 - 29
• Main Authors: Jassim, Doaa Rifaat, Al-Ansari, Ramiz Ahmed, Adil, Ban. H
• Format: Journal Article
• Language: English
• Published: 2023
• ISSN: 1947-5764
• DOI: 10.1615/PlasmaMed.2023049445

Cu:Se core-shell nanomaterials were created using atmospheric cold plasma in order to treat parasite leishmaniasis. In this investigation, leishmania parasite treatment was examined experimentally (Leishmania tropica). Specifically, a 1mm diameter high-voltage electrode was used to produce atmospheric pressure non-thermal plasma. Cu:Se nanoparticles (NPs) were made using copper and selenium salts in aqueous solution as a precursor. The NPs were examined using X-ray diffraction, ultraviolet spectroscopy, and field emission scanning electron microscopy (FESEM). The ideal concentration (3:7) yields grains with a diameter of 17 nm. Morphology of the Cu:Se NPs was studied with FESEM. Observations show that the synthesized NPs were spherical (cluster) in shape with diameters of 15-50 nm, the samller size the samller size of NPs was the best for treatment of NPs was the best for treatment of parasitic leishmaniasis were created. After 48 h of exposure, the percentage of L. tropica parasites for the parasites at a molar concentration of 3:7, 30 min of Cu salt exposure, and 10 min of Se salt exposure, was equal to 78.8%. The core-shell NPs are a viable method for treating the parasite leishmaniasis that threatens people all over the world, according to the results.