Parcijalna resekcija slezine i spleno-renalni sant u lecenju portne hipertenzije sa splenomegalijom i hipersplenizmom

• Published in: Acta chirurgica Iugoslavica Vol. 49; no. 3; pp. 93 - 98
• Main Authors: Radevic, Bozina, Jesic, R., Sagic, Dragan, Perisic, V., Nenezic, D., Popov, P., Ilijevski, Nenad, Dugalic, V., Gajin, P., Vucurevic, G., Radak, Djordje, Trebjesanin, Z., Babic, D., Kastratovic, D., Matic, P.
• Format: Journal Article
• Language: English
• Published: 2002
• ISSN: 0354-950X; 2406-0887
• DOI: 10.2298/ACI0203093R

Some of serious hepatic diseases with cirrhosis may be complicated by portal hypertension, splenomegaly and hypersplenism. Splenomegaly inhibits regenerative processes of the liver, and also intensifies sequestration of the cellular components of blood up to hypersplenism. Cytopenia caused by hypersplenism is aggravated by negative hepatic influence on bone marrow activity-hemathopoesis, and also by recurrent bleeding from oesophageal varices, and from the other site of gastrintestinal tract. This circle of pathologic conditions may be interrupted only by liver transplantation, until which patients are jeopardized by acute bleeding and chronic anemia. Partial resection of the spleen and splenorenal shunt may correct portal hypertension and hypersplenism, prevent gastrointestinal bleeding, and alleviate hepatic regenerative processes inhibition. In this study, 51 patients with partial resection of the spleen and splenorenal shunt, were analyzed. Portna hipertenzija, splenomegalija i hipersplenizam se javljaju kao komplikacije nekih teskih oboljenja jetre sa cirozom. Splenomegalija inhibira regenerativne procese jetre i pojacava sekvestraciju celularnih elemenata krvi do simptomatskog hipersplenizma. Citopeniju zbog hipersplenizma pogorsava negativni uticaj jetre na hematopoezu u kostnoj srzi, kao i ponovljena krvarenja iz variksa jednjaka i drugih partija gastrointestinalnog trakta. Ovaj krug bolesnih stanja moze prekinuti samo transplantacija jetre, a do nje bolesnika ugrozavaju akutno iskrvarenje i hronicna anemija. Parcijalna resekcija slezine i splenorenalni sant koriguju portnu hipertenziju i hipersplenizam, preveniraju gastrointestinalna krvarenja i ublazavaju inhibiciju regenerativnih procesa jetre. U ovom radu su analizirani rezultati 51 bolesnika kod kojih su uradjeni parcijalna resekcija slezine i splenorenalni sant.