Ischemic Stroke in Men Aged 18–50 Years

• Published in: Neuroscience and behavioral physiology Vol. 54; no. 5; pp. 660 - 666
• Main Authors: Pizov, N. A., Baranova, N. S.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2024; Springer Nature B.V
• Subjects: Behavioral Sciences; Biomedical and Life Sciences; Biomedicine; Coronaviruses; COVID-19; Diabetes mellitus; Dyslipidemia; Ischemia; Neurobiology; Neuroimaging; Neurosciences; Original Research; Risk factors; Stroke; cardioembolic subtype; atherothrombotic subtype; risk factors; young age; men; lacunar subtype
• ISSN: 0097-0549; 1573-899X
• DOI: 10.1007/s11055-024-01646-2

Objectives. To evaluate the main modifiable risk factors for the development of ischemic stroke (IS) and the features of the course of the atherothrombotic, cardioembolic, and lacunar subtypes in men aged 18–50 years. Materials and methods. The study included 125 men (mean age 42.6 ± 5.3 years) who were admitted to the Vascular Center before the new coronavirus infection (COVID-19) pandemic and survived the first 30 days after IS. Information on patients’ background characteristics, traditional vascular risk factors, and lifestyle risk factors was collected systematically. Neuroimaging, ultrasound studies, and laboratory investigations were carried out. Results. The atherothrombotic subtype of IS was identified in 60 patients, the lacunar in 46, and the cardioembolic in 19. The main risk factors in the group as a whole included arterial hypertension (83.2%), dyslipidemia (50.4%), smoking (67.2% ), alcohol consumption (29.6%), obesity (16.8%), cardiac dysrhythmias (12%), and diabetes mellitus (8%). Conclusions. The present study in men aged 18–50 years with clearly defined atherothrombotic, lacunar, and cardioembolic subtypes of stroke identified the main risk factors, which had different frequencies depending on stroke subtype and patients’ age.