Comparison of Analgesic effects between Interpleural Bupivacaine with Adrenaline and Interpleural Bupivacaine with Adrenaline & Clonidine in Laparoscopic Cholecystectomy

Additive effect of Clonidine to local anesthetics can be explained by various mechanisms, á-2 agonists form their antinociceptive effects probably by affecting descending noradrenergic tract in spinal cord that plays an important role in pain modulation by anon-opioidmechanism.15 In our study mean t...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of contemporary surgery Vol. 1; no. 2; pp. 36 - 41
Main Authors Nazir, Ovais, Wani, Mushtaq A, Kapoor, B B
Format Journal Article
LanguageEnglish
Published New Delhi Dr. R.K. Sharma 01.07.2013
Institute of Medico-Legal Publications
Subjects
Adrenaline
Advantages
Analgesia
Analgesics
Bupivacaine
Clonidine
Pain management
Studies
Surgery
VAS
Online AccessGet full text

Cover

More Information
Summary:Additive effect of Clonidine to local anesthetics can be explained by various mechanisms, á-2 agonists form their antinociceptive effects probably by affecting descending noradrenergic tract in spinal cord that plays an important role in pain modulation by anon-opioidmechanism.15 In our study mean time of onset of analgesia was 30min in group II, mean time for rescue analgesic or duration of analgesia was 8.26hrs.These findings in our study after a single shot of bupivacaine with adrenaline are consistent with study of Stromskag et al (1988)16 which showed complete relief of pain by 15-30min, mean duration of analgesia with20ml 0.5%was 8hrs . [...]clonidine is a good adjuvant to 0.5% bupivacaine in interpleural block for postoperative analgesia in cases of laparoscopic cholecystectomy without increased incidence of adverse affects.
ISSN:2320-9615
2321-1024
DOI:10.5958/j.2321-1024.1.2.026