Serum Contents of Sialic Acids in Mice Bearing Different Tumors

Sialic acids are the derivatives of aminosugar whose parental structures are formed by nine carbons. Recently, the sialic acids have been found to be related to cell malignancy, i.e. the increasing amount of sialic acids on cell membrane, the types of sialic acids, sialyltransferase activity, and si...

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Published in中国科学通报：英文版 no. 14; pp. 1220 - 1223
Main Author 卢大用 梁罡 张明坚 胥彬
Format Journal Article
LanguageEnglish
Published 01.07.1994
Subjects
acids
antineoplastic
carcinogeneses
drugs
HPLC
metastases
neoplasm
sialic
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Summary:Sialic acids are the derivatives of aminosugar whose parental structures are formed by nine carbons. Recently, the sialic acids have been found to be related to cell malignancy, i.e. the increasing amount of sialic acids on cell membrane, the types of sialic acids, sialyltransferase activity, and sialyltransferase inhibitor can inhibit the tumor metastases. This work tries to explore the tumor-sialic acid relation and the influences of antineoplastic drugs on free sialic acids in mice sera by means of HPLC.
Bibliography:11-1785/N
LU Da-Yong LIANG Gang ZHANG Ming-JianXU Bin(Shanghai University of Science and Technology, Shanghai 201800, PRC)Shanghai Institute of Materia Medica,Academia Sinica,Shzngai 20031,PRC
ISSN:1001-6538
1861-9541