Mucocutaneous Features of Pemphigus Vulgaris and its Management - A Case Report

Pemphigus vulgaris is a chronic vesicular-ampullar mucocutaneous disease that almost always produces oral manifestations. The pemphigus diseases are a group of antibody mediated disorders that manifest as blistering conditions of the skin and/or mucus membranes. This is a case report of a 40 year ol...

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Bibliographic Details
Published inIndian journal of contemporary dentistry Vol. 1; no. 2; pp. 44 - 48
Main Authors Gupta, Manish, Devi, Parvathi, Aggarwal, Avanti
Format Journal Article
LanguageEnglish
Published New Delhi Dr. R.K. Sharma 01.07.2013
Institute of Medico-Legal Publications
Subjects
Autoantibodies
Chronic illnesses
Corticosteroids
Dermatology
Drug dosages
Geriatrics
Immunoflourescence
Intralesional Steroids
Mortality
Patients
Pemphigus
Systemic Steroids
Ulcers
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Summary:Pemphigus vulgaris is a chronic vesicular-ampullar mucocutaneous disease that almost always produces oral manifestations. The pemphigus diseases are a group of antibody mediated disorders that manifest as blistering conditions of the skin and/or mucus membranes. This is a case report of a 40 year old female patient who presented with a six month history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with Pemphigus vulgaris. Intralesional corticosteroids were instituted and marked improvement was noted. Chronic oral ulcerations can be the sole manifestation of Pemphigus vulgaris, atleast initially, that can be subsided by the use of intralesional corticosteroids. Early recognition of this lesion may prevent delayed diagnosis and inappropriate treatment of a potentially chronic dermatological condition.
ISSN:2320-5806
2320-5962
DOI:10.5958/j.2320-5962.1.2.030