Chemotherapy-induced Toxic Leukoencephalopathy

Leukoencephalopathy is characterized by progressive structural damage in the white matter, mainly due to myelin damage. Metabolic, toxic and infectious agents may cause leukoencephalopathy. Several chemotherapeutic agents, especially methotrexate and 5-fluorouracil (5-FU), have been shown to be asso...

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Published inTürk nöroloji dergisi Vol. 26; no. 1; pp. 49 - 52
Main Authors Yetkin, Mehmet Fatih, Göl, Mehmet Fatih, Köse, Elif Gülşen, Kaynar, Leylagül
Format Journal Article
LanguageEnglish
Published Türk Nöroloji Derneği 01.03.2020
Subjects
Tıp
Ankara
Türkiye
methotrexate
primer merkezi sinir sistemi lenfoması
metotreksat
Leukoencephalopathy
primary central nervous system lymphoma
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Summary:Leukoencephalopathy is characterized by progressive structural damage in the white matter, mainly due to myelin damage. Metabolic, toxic and infectious agents may cause leukoencephalopathy. Several chemotherapeutic agents, especially methotrexate and 5-fluorouracil (5-FU), have been shown to be associated with leukoencephalopathy.
ISSN:1301-062X
1309-2545
DOI:10.4274/tnd.2019.12369