29. Morphological spectrum of renal involvement in plasma cell dyscrasias

Different morphologic patterns of kidney damage are seen in patients with plasma cell dyscrasias. This is a retrospective review of 6 cases of renal involvement in plasma cell dyscrasias, out of 71 renal biopsies reported in the Gold Coast Hospital from July 2011 to April 2012. The primary diagnoses...

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Published inPathology Vol. 45; p. S113
Main Authors Nigam, S., Ortiz Gomez, J.D., Wright, G.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 2013
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Summary:Different morphologic patterns of kidney damage are seen in patients with plasma cell dyscrasias. This is a retrospective review of 6 cases of renal involvement in plasma cell dyscrasias, out of 71 renal biopsies reported in the Gold Coast Hospital from July 2011 to April 2012. The primary diagnoses included multiple myeloma (5) and MGUS (1). There were 4 males and 2 females. The age range was 54–91 years, mean age being 71 years. The renal biopsies showed amyloidosis, monoclonal immunoglobulin deposition disease, myeloma cast nephropathy, immunotactoid glomerulopa-thy, proximal tubulopathy with acquired Fanconi syndrome and kappa light chain related proximal tubulopathy with acute tubular injury. Their clinical and pathological features including light microscopy, immunofluorescence and electron microscopy with a review of the literature is discussed.
ISSN:0031-3025
1465-3931
DOI:10.1097/01.PAT.0000427029.02536.86