STUDIES ON MOUSE LEUKEMIA

The effect of heat, hypo- and hypertonic salt solutions, glycerin, desiccation, and mechanical injury was studied on leukemic lymphoid cells of the mouse, and the leukemia-transmitting property of cell suspensions (hypothetical transmitting agent) in vitro. The results indicate that leukemia has not...

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Bibliographic Details
Published inThe Journal of experimental medicine Vol. 57; no. 1; pp. 1 - 20
Main Authors Richter, Maurice N., MacDowell, E. C.
Format Journal Article
LanguageEnglish
Published 01.01.1933
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Summary:The effect of heat, hypo- and hypertonic salt solutions, glycerin, desiccation, and mechanical injury was studied on leukemic lymphoid cells of the mouse, and the leukemia-transmitting property of cell suspensions (hypothetical transmitting agent) in vitro. The results indicate that leukemia has not been transmitted by inoculation without the introduction of living cells. The interval between inoculation and death bears an inverse relationship to the number of living cells inoculated.
ISSN:0022-1007
1540-9538
DOI:10.1084/jem.57.1.1