Multimodal treatment of patients with advanced cervical cancer

• Published in: Bukovinian Medical Herald Vol. 18; no. 3 (71)
• Main Authors: O. V. Lukianchuk, V. V. Lysenko, M. A. Lysenko
• Format: Journal Article
• Language: English
• Published: 02.09.2014
• ISSN: 1684-7903; 2413-0737
• DOI: 10.24061/2413-0737.XVIII.3.71.2014.145

Local progressive tumor growth involving the urinary tract with no distant metastases is known to be one of the features of cervical cancer in the advanced stages. Approximately 68 % of patients in stage T3-T4 have various uroevolution disorders. The severity of their condition often is caused by an increasing renal failure or a fever, those are associated with obstructive pyelonephritis and often are interpreted as the carcinogenic intoxication. Therefore, any special antineoplastic therapy methods are considered as unpromising even for patients without concomitant diseases. The authors conducted a retrospective analysis of 11 patients with the treatment of advanced non-metastatic cervical cancer, which included both surgery and neoadjuvant polychemotherapy (PCT). Our results demonstrate the advisability of multimodal phasing treatment of those patients, compared with palliative radiotherapy and symptomatic treatment.