Synthesis, Spectral Studies Antibacterial and Antifungal Activity of 2"-Amino-4"-[2 -(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridin-3-yl]-6"-Aryl Nicotinonitrile
Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitr...
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Published in | International letters of chemistry, physics and astronomy Vol. 49; pp. 161 - 166 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
01.04.2015
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Online Access | Get full text |
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Summary: | Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitriles ( 4a-4l ) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/ml. The structures of the products have been elucidated by IR,
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H-NMR, Mass spectral data, elemental analysis and thin layer chromatography. |
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ISSN: | 2299-3843 2299-3843 |
DOI: | 10.18052/www.scipress.com/ILCPA.49.161 |