Development of a Mouse Biomagnetic Measurement System by Using a High- T SQUID Magnetometer

We have developed a biomagnetic measurement system for mouse by using high-T C SQUID magnetometer. The system consists of a high-T C SQUID magnetometer, a table-top magnetically shielded box, and a nonmagnetic dewar with a warm-to-cool distance of about 4 mm. Mice with weights of about 27 g were ane...

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Bibliographic Details
Published inIEEE transactions on applied superconductivity Vol. 21; no. 3; pp. 493 - 496
Main Authors Kim, In-Seon, Ahn, San, Lee, Chul-Ho, Lee, Yong-Ho
Format Journal Article
LanguageEnglish
Published IEEE 01.06.2011
Subjects
Biomagnetic measurement
high- T_{\rm C} SQUID magnetometer
Magnetic noise
Magnetic shielding
magnetocardiography
Magnetometers
Magnetosphere
Mice
mouse
SQUIDs
Superconducting magnets
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ISSN1051-8223
1558-2515
DOI10.1109/TASC.2010.2094993

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Summary:We have developed a biomagnetic measurement system for mouse by using high-T C SQUID magnetometer. The system consists of a high-T C SQUID magnetometer, a table-top magnetically shielded box, and a nonmagnetic dewar with a warm-to-cool distance of about 4 mm. Mice with weights of about 27 g were anesthetized and fixed in supine position on a plastic xyz-stage inside the shield box. The SQUID readout signal was digitized in 24-bit and recorded with sampling rate of 1280 Hz. We carried out a scanning measurement by changing x- and y-position of the subject inside the shield box. Finally, we could obtain clear mouse MCG waveforms of about 20 pT in peak amplitude with well defined P-, QRS-, and T-wave. We demonstrated the high-T C SQUID magnetometer based biomagnetic measurement system is useful for monitoring mouse MCG signals with sufficient noise-to-signal ratio.
ISSN:1051-8223
1558-2515
DOI:10.1109/TASC.2010.2094993