Phylodynamic of HCV Populations

Hepatitis C virus is an actual public health problem worldwide since its discovering in 1989. It is explained not only by the wide spreading and frequent adverse outcomes of disease, the lack of effective preventive vaccine, but also by the high genetic variability of the virus. The current review s...

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Published inVestnik Rossiĭskoĭ akademii medits︠i︡nskih nauk no. 5; p. 573
Main Authors Kalinina, O V, Zhebrun, A B
Format Journal Article
LanguageRussian
Published Russia (Federation) 03.12.2015
Subjects
DNA, Viral - genetics
Epidemics
Genotype
Global Health
Hepacivirus - genetics
Hepatitis C - epidemiology
Hepatitis C - virology
Humans
Phylogeny
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Summary:Hepatitis C virus is an actual public health problem worldwide since its discovering in 1989. It is explained not only by the wide spreading and frequent adverse outcomes of disease, the lack of effective preventive vaccine, but also by the high genetic variability of the virus. The current review summarizes the results of phylodynamic and phylogeographic studies of different HCV populations that allowed to characterize epidemic processes, to analyze the divergence of HCV into genotypes and subtypes, and to determine the geographic origin of the current HCV epidemic variants.
ISSN:0869-6047
DOI:10.15690/vramn.v70.i5.1444