Prevalence of Herpes Simplex Virus (HSV) type II antibodies in Human Immunodeficiency Virus (HIV)-infected patients in Benin City, Nigeria

• Published in: International journal of medicine and biomedical research Vol. 6; no. 1; pp. 47 - 58
• Main Authors: Okwara, BU, Eze, EU, Onunu, AN, Kubeyinje, EP, Unuigbe, EU, Okwara, OHN
• Format: Journal Article
• Language: English
• Published: Lagos Michael Joanna Publications 15.03.2017
• Subjects: Antibodies; Confidence intervals; Deoxyribonucleic acid; DNA; Epidemics; Ethnic factors; HIV; Human immunodeficiency virus; Infectious diseases; Informed consent; Itching; Pain; Pruritus; Signs and symptoms; Ulcers; Viruses; United States > US; Benin City Nigeria; Europe; Africa; Uganda; Nigeria; France; North America
• ISSN: 2277-0941; 2315-5019
• DOI: 10.14194/ijmbr.6.1.6

Antibodies, HSV, HIV, seropositivity, epidemic, infectious disease (ProQuest: ... denotes formulae omitted.) INTRODUCTION Herpes simplex virus type 2 (HVS-2), a DNA virus and a sexually transmitted infection (STI), is the major cause of herpes genitalis. [12] The disparities may be due to a variety of factors, both current and historical, which include racial and ethnic differences in the prevalence of poverty and low socio-economic status, access to health care, sexual behaviour, health related behaviour and illicit drug use as well as the age and sex composition of the population. Sample size The sample size was determined using the Fisher's formula ... n = Minimum sample size Z = Normal standard deviation 95% confidence interval = 1.96 p = Prevalenceq = 1-p d = Margin of error (Degree of precision desired) = 0.1 (one-fifth of p) Studies on prevalence of HSV-2 infection described a geographical variation, ranging between 4-80% worldwide. After obtaining an informed consent, a data acquisition sheet (structured questionnaire) was self-administered to collect information, including the presence or absence of symptoms suggestive of HSV-2 infections both in the past and or during the period of study and these include ulcers in the genitalia/gluteal region, mouth and fingers, genital itching, burning sensation or pain on genitalia, mouth or fingers, penile or vaginal discharge and dysuria especially in women.