Effects of quantitative trait loci on chromosomes 1, 2, 4, and 7 on growth, carcass, and meat quality traits in backcross Meishan × Large White pigs1

• Published in: Journal of animal science Vol. 84; no. 3; pp. 526 - 537
• Main Authors: Sanchez, M.-P., Riquet, J., Iannuccelli, N., Gogué, J., Billon, Y., Demeure, O., Caritez, J.-C., Burgaud, G., Fève, K., Bonnet, M., Péry, C., Lagant, H., Le Roy, P., Bidanel, J.-P., Milan, D.
• Format: Journal Article
• Language: English
• Published: Champaign Oxford University Press 01.04.2006
• Subjects: Chromosomes; Confidence intervals; Genetics; Genomics; Hogs; Tests
• ISSN: 0021-8812; 1525-3163
• DOI: 10.2527/2006.843526x

The aim of this work was to estimate whether genetic dissection of QTL on chromosomes 1, 2, 4, and 7, detected in an F^sub 2^ Meishan × Large White population, can be achieved with a recombinant backcross progeny test approach. For this purpose, a first generation of backcross (BC^sub 1^) was produced by using frozen semen of F^sub 1^ Large White × Meishan boars with Large White females. Four BC^sub 1^ boars were selected because of their heterozygosity for at least 1 of the 4 regions. The BC^sub 1^ boars were crossed with Large White sows, and the resulting BC^sub 2^ offspring were measured for several growth and body composition traits. Contrary to the F^sub 2^ animals, BC^sub 2^ animals were also measured for meat quality traits in adductor, gluteus superficialis (GS), longissimus dorsi, and biceps femoris (BF) muscles. Each BC^sub 1^ boar was tested for a total of 39 traits and for the 4 regions with statistical interval mapping analyses. The QTL effects obtained in BC^sub 1^ families showed some differences compared with those described in F^sub 1^ families. However, we confirmed QTL effects for growth in the SW1301-SW2512 markers interval on chromosome 1 and also for body composition in the SW1828-SW2512 markers interval on chromosome 1, in the SW2443-SWR783 markers interval on chromosome 2, and in the SW1369-SW632 markers interval on chromosome 7. In addition, we detected new QTL for growth traits on chromosome 2 and for meat quality traits on chromosomes 1 and 2. Growth of animals from weaning to the end of the test was influenced by the IGF2 gene region on chromosome 2. Concerning meat quality, ultimate pH of adductor, longissimus dorsi, and BF were affected by the interval delimited by UMNP3000 and SW2512 markers on chromosome 1, and a* of GS, L* of BF, and water-holding capacity of GS were affected by QTL located between marker loci SW2443 and SWR783 on chromosome 2. Recombinant progeny testing appeared to be a suitable strategy for the genetic dissection of the QTL investigated. [PUBLICATION ABSTRACT]