Six noreudesmane sesquiterpenoids from Dobinea delavayi and their lipid-lowering and antimalarial activities

• Published in: Journal of molecular structure Vol. 1321; p. 140066
• Main Authors: Dong, Li-Tian, Chen, Wei, He, Pei-Mi, Sun, He, Liu, Bo-Chao, Zhao, Xuan, Liu, Rong, Shen, Lei, Jiang, Bei, Xiao, Chao-Jiang
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 05.02.2025
• Subjects: Anacardiaceae; Antimalarial activities; Chemical constituents; Dobinea delavayi; Isolation and identification; Lipid-lowering; Noreudesmane sesquiterpenoids; Chemical constituents; Isolation and identification; Dobinea delavayi; Antimalarial activities; Lipid-lowering; Anacardiaceae; Noreudesmane sesquiterpenoids

•Dobinin V is the first example of 7,8-seco-11,12,13-trinoreudesmane sesquiterpenoid in nature.•A possible biosynthetic pathway of dobinins V−Z, and AA is proposed.•Lipid-lowering activity of eudesmane sesquiterpenoids was first discovered.•Dobinin AA showed significant in vitro lipid-lowering activ...