Clinical Characteristics And Outcomes Of Patients With Heart Failure Of Hypertensive Etiology: Analysis Of The Colombian Registry Of Heart Failure

• Published in: Journal of cardiac failure Vol. 29; no. 4; pp. 637 - 638
• Main Authors: Echeverria, Luis Eduardo, Martinez, Erika, Gomez-Mesa, Juan, Rivera-Toquica, Alex, Zarama, Mario, Ramírez, Elkin Giovanni, Bustamante, Rafael, Palacio, Rolando, Ávila, Luis, Campbell, Sebastián, Morales, Lisbeth Natalia, Lopez, Juan David, Buitrago, Andres, Sandoval, Jorge, Saldarriaga, Clara
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.04.2023
• ISSN: 1071-9164; 1532-8414
• DOI: 10.1016/j.cardfail.2022.10.223

Hypertension represents one of the main comorbidities observed in patients with Heart Failure (HF), being, in turn, one of the main risk factors for its development. Studies evaluating this etiological entity individually are scarce in Latin America. Our objective was to analyze the prevalence of HF of hypertensive etiology and evaluate its prognosis in patients enrolled in the Colombian Heart Failure Registry (RECOLFACA). RECOLFACA recruited adult patients diagnosed with HF in 60 centers in Colombia from 2017 to 2019. The primary outcome was all-cause mortality. A Cox proportional hazards regression model was used to evaluate the factors associated with the primary outcome in patients with HF of hypertensive origin. A value of p <0.05 was considered significant. All statistical tests were two-tailed. Of the total number of patients evaluated in RECOLFACA (n=2514), 804 (31.9%) had a diagnosis of HF of hypertensive origin. Patients with hypertensive cardiomyopathy were less frequently male, significantly older, and had a lower prevalence of comorbidities than those with HF of other etiologies. Additionally, patients with hypertensive HF had a higher prevalence of HF with preserved ejection fraction (34.1% vs. 28.3%; p=0.004). Finally, type 2 diabetes mellitus, a diagnosis of COPD, and a NYHA IV classification were identified as independent risk factors for mortality in these patients. HF of hypertensive origin represents about a third of all patients with HF in the Colombian Heart Failure Registry, presenting a differential clinical profile with a predominance of HF with a preserved ejection fraction