510-P: Prevalence of Mental, Behavioral, and Developmental Disorders among Youth with Diabetes, United States (2016-2019)

• Published in: Diabetes (New York, N.Y.) Vol. 70; no. Supplement_1
• Main Authors: BARRETT, CATHERINE E., BULLARD, KAI M., PARK, JOOHYUN, KOYAMA, ALAIN, MERCADO, CARLA, CLAUSSEN, ANGELIKA H., NEWSOME, KIM, PAVKOV, MEDA E.
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 01.06.2021
• Subjects: Attention deficit hyperactivity disorder; Autism; Children; Children & youth; Chronic illnesses; Diabetes; Diabetes mellitus; Gilles de la Tourette syndrome; Hyperactivity; Intellectual disabilities; Neurodevelopmental disorders; Quality of life; Speech; Speech disorders; Tourette syndrome; United States > US
• ISSN: 0012-1797; 1939-327X
• DOI: 10.2337/db21-510-P

Diabetes (DM) is among the most common chronic diseases diagnosed in youth in the United States. In adults, a bi-directional relationship has been demonstrated between DM and mental, behavioral, and developmental disorders (MBDD). Such comorbidities may significantly impact the quality of life of patients with DM and disease management. However, little is known about the association of DM and MBDD in youth. To examine the magnitude of overlap between these chronic conditions, we calculated prevalence estimates using the 2016-2019 National Survey of Children’s Health, an annual, cross-sectional survey of non-institutionalized US children aged 0-17 years (N = 131,774). Parents were asked if their child was ever diagnosed with DM or with any of the following MBDDs: attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, learning disability, intellectual disability, developmental delay, anxiety, depression, behavioral or conduct problems, Tourette syndrome, or speech disorder. We present crude prevalence estimates and predictive margins adjusted for age, sex, and race/ethnicity, both weighted to be representative of the US youth population. Among US youth, prevalence estimates were 0.45% (95%CI: 0.36-0.55) for DM and 22.7% (22.2-23.2) for any MBDD. Crude prevalence of any MBDD varied by DM status (DM: 43.7% [34.5-53.4]; no DM: 22.6% [22.1-23.1]). Compared with youth without DM, those with DM had a higher adjusted prevalence of any MBDD (prevalence ratio: 1.55 [1.20-2.00]) and individual MBDDs (p <.05), except for ADHD, Tourette syndrome and speech disorder. These results suggest a significant health burden with more than 2 out of 5 youth with DM having any MBDD. Future work examining potential causal pathways could be beneficial. Understanding associated factors may ultimately lead to future preventative strategies for MBDD and DM in youth.