ISCHEMIC COLITIS IN AN ADULT PATIENT WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME (case report)

Atypical hemolytic uremic syndrome (aHUS) is a rare life-threatening condition caused by uncontrolled complement activation due to mutations in the alternative pathway of complement components. aHUS is characterized by microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure and affe...

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Published inKoloproktologia Vol. 18; no. 2; pp. 82 - 89
Main Authors Ozerova, O. S., Poltorykhina, E. A., Vardanyan, A. V., Maynovskaya, O. A., Veselov, V. V., Chernyshov, S. V.
Format Journal Article
LanguageEnglish
Published 19.06.2019
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Summary:Atypical hemolytic uremic syndrome (aHUS) is a rare life-threatening condition caused by uncontrolled complement activation due to mutations in the alternative pathway of complement components. aHUS is characterized by microangiopathic hemolytic anemia, thrombocytopenia, acute renal failure and affecting multiple organ systems. Extra-renal manifestations of aHUS take place in 20% of patients including involvement of the central nervous system, cardiovascular system, lungs, skin and gastrointestinal tract. This case report describes a severe course of atypical hemolytic uremic syndrome in a 21-year-old female, developed ischemic colitis.
ISSN:2073-7556
DOI:10.33878/2073-7556-2019-18-2-82-89