Baculovirus system for foreign genes expression - present and future of biotechnology receaving of biologically active proteins of various origin

Recombinant baculoviruses have became popular expression vectors for heterologous proteins. This review deals with the current status and potential use of baculovirus vectors for the expression of foreign genes in insect cells. Advantages of this invertebrate virus expression vector comparing with b...

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Bibliographic Details
Published inBiopolimery i kletka Vol. 10; no. 5; pp. 31 - 48
Main Authors Kikhno, I. M., Strokovskaya, L. I.
Format Journal Article
LanguageEnglish
Published Kiev Natsional'na Akademiya Nauk Ukrainy - National Academy of Sciences of Ukraine 20.09.1994
Subjects
Biological activity
Biotechnology
Expression vectors
Insect cells
Invertebrates
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Summary:Recombinant baculoviruses have became popular expression vectors for heterologous proteins. This review deals with the current status and potential use of baculovirus vectors for the expression of foreign genes in insect cells. Advantages of this invertebrate virus expression vector comparing with bacterial, yeast and mammalian system are proved. Trends in the development of transfer vectors for the expression of heterologus genes and strategies for maximizing levels of expression are discussed.
ISSN:0233-7657
1993-6842
DOI:10.7124/bc.0003BA