N-doped antioxidant carbon dots as a bimodal probe for nitrite detection in commercial meat products

Accurate, sensitive, and specific nitrite ion (NO2−) detection is critical for maintaining the quality of food and water, given its ubiquitous presence in the environment. This investigation introduces the development of nitrogen-infused carbon dots, which serve dual functions as antioxidants and NO...

Full description

Saved in:
Bibliographic Details
Published inDiamond and related materials Vol. 149; p. 111624
Main Authors Alkaltham, Mohammed S., Althawab, Suleiman A., Alsulami, Tawfiq, Alzahrani, Abdulhakeem
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.11.2024
Subjects
Antioxidant activity
Bimodal detection
Biocompatibility
Carbon dots
Colorimetry
Fluorescence
Nitrite
Antioxidant activity
Fluorescence
Biocompatibility
Colorimetry
Carbon dots
Nitrite
Bimodal detection
Online AccessGet full text

Cover

More Information
Summary:Accurate, sensitive, and specific nitrite ion (NO2−) detection is critical for maintaining the quality of food and water, given its ubiquitous presence in the environment. This investigation introduces the development of nitrogen-infused carbon dots, which serve dual functions as antioxidants and NO2−sensors in food products. These carbon dots (CDs) facilitates bimodal NO2− detection, combining precise fluorimetric detection and straightforward colorimetric analysis. Upon introduction into the solution, NO2− interacts with the amino groups on the surface of the CDs, resulting in the formation of a diazotized compound and causing a color change in the solution. Notably, the detection limits for NO2− are determined to be 0.19 μM and 0.144 μM, respectively. In addition, the bimode probe demonstrates exceptional consistency and recovery in determining NO2− concentrations in commercial samples. The radical scavenging activity of the CDs is assessed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) tests, revealing robust antioxidant activity (~78 % DPPH) and (>80 % for ABTS). Furthermore, cell viability is evaluated through the metabolic activity of fibroblast (NIH 3 T3) cells. Due to their antioxidant properties and low toxicity to human cell lines, these CDs represent a versatile and useful tool for biomedical research. [Display omitted]
ISSN:0925-9635
DOI:10.1016/j.diamond.2024.111624