Some Problems of Membrane Plasma Separation

• Published in: IFAC Proceedings Volumes Vol. 15; no. 2; pp. 107 - 112
• Main Authors: Piątkiewicz, W., Judycki, W., Nałęcz, M., Stryjecka-Rowińska, D., Orłowski, T.
• Format: Journal Article
• Language: English
• Published: 01.05.1982
• Subjects: Mathematical modelling; plasma filtering; separator; sieving coefficient; transmembrane pressure control; transmembrane pressure control; Mathematical modelling; plasma filtering; sieving coefficient; separator
• ISSN: 1474-6670
• DOI: 10.1016/S1474-6670(17)63303-2

The membrane plasma filtration devices are the ones of the most atractive scientific subjects in the area of artificial organs. The possible application of this technique is very wide in the field of bioengineering and also play an important role in contemporary medicine. In order to evaluate this problem the simple mathematical model of capillary plasma filtration including the Blackshear-Forstrom theory was evaluated. The limitation of plasma outflow from the blood cells deposition is discussed. Based on the conclusions coming out from this analysis the controller of mean transmembrane pressure MTP was constructed and evaluated to standardize the conditions of the filtration process. The controll problems of membrane plasma separation in close loop circuit is discussed. The experimental mechanical and chemical data of the plasma separation in "ex vivo" conditions clinical evaluation are presented and analyzed from the sieving coefficient point of view. The method of controlling the membrane plasma separation process by means of filtration rate is suggested and compared with the driving criterion of mean transmembrane pressure from the filter sieving properties point of view.