Assessment of fixation stability and ocular torsion in a patient with ciancia syndrome: Case report

• Published in: Acta ophthalmologica (Oxford, England) Vol. 103; no. S284
• Main Authors: Ramón‐Campillo, Aida, Gimeno, Inmaculada Bueno, Sampedro, Andrés Gené
• Format: Journal Article
• Language: English
• Published: Malden Wiley Subscription Services, Inc 01.01.2025
• Subjects: Case reports; Children; Childrens health; Eye; Ophthalmology; Patients; Physiology; Retina; Retinography; Sensorimotor integration; Strabismus; Visual system
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/aos.17151

Aims/Purpose: This study, performed as a clinical case, was carried out with the aim of evaluating fixation stability by means of the MAIA microperimeter and the presence of ocular torsion by retinography in a patient with Ciancia syndrome. Methods: Two subjects both 24 years old were selected, one without visual system alterations, and the other with Ciancia syndrome, operated three times in childhood for strabismus, leaving 30 DP of residual Endotropia (ET). Fixation stability was assessed using the MAIA microperimeter by performing two tests, an expert examination and a fixation stability test for 30 seconds. Torsion was evaluated by performing retinography with the Topcon MAESTRO‐2 device and measuring the disc‐fovea angle (DFA). Results: The patient with Ciancia syndrome had fixation stability within normal limits but a greater number and amplitude of microsaccadic fixations, as well as a greater number of refixations, compared to the normal subject. Additionally, the strabismic subject presented physiological torsion in the right eye (RE) (2°) and exciclotorsion in the left eye (LE) (11°), while the normal subject presented physiological torsion within the norm in both eyes RE (8°) and LE (2°). Conclusions: Early treatment of Ciancia Syndrome in children improves visual and motor development, providing the patient achieves normal fixation stability. However, patients exhibit many microsaccadic movements and refixations to maintain a fixed gaze. Early treatment also reduces ocular torsion caused by muscular alterations. References Milla‐Barrios M, Piñero DP, Molina‐Martín A. Fixation Pattern Analysis With Microperimetry In Strabismic Subjects: A Pilot Study. Seminars in Ophthalmology 2022 ‐06‐06;37(6):699. Khanna RK, Pasco J, Santallier M, Pisella PJ, Arsene S. Objective ocular torsion outcomes after unilateral horizontal rectus surgery in infantile esotropia. Graefe's Archive for Clinical and Experimental Ophthalmology. 2018 Sep 1;256(9):1783–8.