A Comparison of 18F-PSMA-1007 and 64Cu-PSMA in 2 Patients With Metastatic Prostate Cancer

18F-prostate-specific membrane antigen (PSMA) 1007 is one of the most promising radiotracers for PET imaging in prostate cancer, minimal urinary clearance, and higher spatial resolution, which are the most outstanding features. PSMA can also be labeled with 64Cu, offering a longer half-life and diff...

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Bibliographic Details
Published inClinical nuclear medicine Vol. 47; no. 2; p. e120
Main Authors Cardoza-Ochoa, David R, Rivera-Bravo, Belén
Format Journal Article
LanguageEnglish
Published United States 01.02.2022
Subjects
Copper Radioisotopes
Gallium Radioisotopes
Humans
Male
Niacinamide - analogs & derivatives
Oligopeptides
Positron Emission Tomography Computed Tomography
Prostatic Neoplasms
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Summary:18F-prostate-specific membrane antigen (PSMA) 1007 is one of the most promising radiotracers for PET imaging in prostate cancer, minimal urinary clearance, and higher spatial resolution, which are the most outstanding features. PSMA can also be labeled with 64Cu, offering a longer half-life and different resolution imaging. We present images of metastatic prostate cancer in two patients, where 64Cu-PSMA PET/CT was performed one day after 18F-PSMA-1007 PET/CT. In the two patients, both radiotracers provided high image quality and a similar range of detection for metastatic lesions.
ISSN:1536-0229
DOI:10.1097/RLU.0000000000003758