In-Home Intravenous Dexmedetomidine Infusion for Treatment of Dystonia: A Pediatric Case Report

The off-label use of an intravenous dexmedetomidine infusion is an option for refractory symptoms in pediatric palliative care with a few published cases of in-home use, most limited to end-of-life care. After an intrathecal baclofen pump malfunction with meningitis and medication withdrawal, a 17-y...

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Bibliographic Details
Published inA&A practice Vol. 18; no. 9; p. e01851
Main Authors Richner, Gwendolyn J, Allen, Stephanie S, Adair, Lindsay M, Grossoehme, Daniel H, Kelly-Langen, Catherine A, McNair, Wendy J, Williams, Madelyne L, Friebert, Sarah
Format Journal Article
LanguageEnglish
Published United States 01.09.2024
Subjects
Adolescent
Baclofen - administration & dosage
Cerebral Palsy - complications
Cerebral Palsy - drug therapy
Dexmedetomidine - administration & dosage
Dystonia - drug therapy
Home Infusion Therapy
Humans
Infusions, Intravenous
Male
Palliative Care
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Summary:The off-label use of an intravenous dexmedetomidine infusion is an option for refractory symptoms in pediatric palliative care with a few published cases of in-home use, most limited to end-of-life care. After an intrathecal baclofen pump malfunction with meningitis and medication withdrawal, a 17-year-old adolescent with quadriparetic cerebral palsy and paroxysmal autonomic instability experienced relief of refractory pain and dystonia with an in-home intravenous dexmedetomidine infusion. His interdisciplinary care team collaborated to establish safety measures and adjust his home medication regimen to further improve quality of life well before his end of life.
ISSN:2575-3126
DOI:10.1213/XAA.0000000000001851