Optimization of antisecretory component of severe acute pancreatitis intensive management

• Published in: Hirurgija (Moskva) no. 6; p. 83
• Main Authors: Alexandrova, E D, Sadchikov, D V, Kuligin, A V
• Format: Journal Article
• Language: English; Russian
• Published: Russia (Federation) 2016
• Subjects: Critical Care - methods; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination - methods; Endotoxemia - etiology; Endotoxemia - therapy; Female; Fluid Therapy - methods; Gastrointestinal Agents - administration & dosage; Humans; Length of Stay; Male; Middle Aged; Octreotide - administration & dosage; Pancreatitis, Acute Necrotizing - complications; Pancreatitis, Acute Necrotizing - diagnosis; Pancreatitis, Acute Necrotizing - physiopathology; Pancreatitis, Acute Necrotizing - therapy; Treatment Outcome
• ISSN: 0023-1207
• DOI: 10.17116/hirurgia2016683-85

Improvement of complex intensive care of severe acute pancreatitis with use of continued intravenous infusion of octreotid. 85 patients with severe acute pancreatitis were involved into the investigation, were divided into 2 groups. Patients of the control group (44 patients) got an intensive care according to severe acute pancreatitis treatment. Complex intensive treatment of the group of comparison (41 patients) included injections of octreotid (300 mcg 3 times a day). The change of octreotid usege scheme allowed to improve treatment resultes, wchis is the decrease of endotoxemia level and minimization of time spent at emergency department.