Triponderal mass index and markers of metabolic risk in children and adolescents with obesity
Triponderal mass index (TMI) would estimate excess adiposity better than body mass index (BMI), maintaining stable values during childhood. This work aims to determine the correlation between TMI and markers of metabolic risk as well as set values of TMI that are related to an increase of metabolic...
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Published in | Medicina clínica (English ed.) Vol. 160; no. 9; pp. 379 - 384 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier España, S.L.U
12.05.2023
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Subjects | |
Online Access | Get full text |
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Summary: | Triponderal mass index (TMI) would estimate excess adiposity better than body mass index (BMI), maintaining stable values during childhood. This work aims to determine the correlation between TMI and markers of metabolic risk as well as set values of TMI that are related to an increase of metabolic risk.
Multicenter, observational, cross-sectional and prospective study in children under 14 years of age with obesity. Variables: age, sex, pubertal stage, weight, height, abdominal circumference, BMI, TMI, basal glucose and insulin, HOMA index, blood pressure, lipoprotein profile, transaminases and uric acid. BMI and TMI were expressed according to the values of the Barcelona Longitudinal Study. Statistical analysis was performed with the SPSS® program.
199 patients (50.3% male), age 11.08 (2.48) years, TMI 19.68 (2.36) kg/m3. Correlation between TMI and abdominal circumference (r 0.571; p 0), insulin (r 0.198; p 0.005), HOMA index (r 0.189; p 0.008) and HDL-c (r −0.188; p 0.008) was observed. IMT>20.15kg/m3 was associated with insulin ≥15 mIU/mL (p 0.029) and IMT>20.36kg/m3 with HDL-c <40mg/dl (p 0.023).
TMI was correlated with increase of abdominal circumference, insulin and HOMA index and decrease of HDL-c. IMT>20kg/m3 can be associated with increased insulin and decreased HDL-c. Therefore, the IMT seems to be a useful parameter in the assessment of pediatric patients with obesity.
El índice de masa triponderal (IMT) estimaría mejor que el índice de masa corporal (IMC) el exceso de adiposidad manteniendo valores estables durante la infancia. Este trabajo pretende determinar la correlación del IMT con marcadores de riesgo metabólico y establecer valores del IMT que se relacionen con un aumento del riesgo metabólico.
Estudio multicéntrico, observacional, transversal y prospectivo en menores de 14 años con obesidad. Variables: edad, sexo, estadio puberal, peso, talla, perímetro abdominal, IMC, IMT, glucosa e insulina basales, índice HOMA, presión arterial, perfil lipoproteico, transaminasas y ácido úrico. El IMC y del IMT se expresaron según los valores del Estudio longitudinal de Barcelona. Se realizó análisis estadístico con el programa SPSS®.
199 pacientes (50,3% varones), edad 11,08 (2,48) años, IMT 19,68 (2,36) kg/m3. Se observó correlación del IMT con perímetro abdominal (r 0,571; p 0), insulina (r 0,198; p 0,005), índice HOMA (r 0,189; p 0,008) y HDL-c (r −0,188; p 0,008). El IMT>20,15kg/m3 se asoció a insulina ≥15 mUI/mL (p 0,029) y el IMT>20,36kg/m3 a HDL-c <40mg/dl (p 0,023).
El IMT se correlacionó con el incremento del perímetro abdominal, la insulina y el índice HOMA y la disminución del c-HDL. El IMT>20kg/m3 puede asociarse a elevación de la insulina y a descenso del c-HDL. Por ello, el IMT parece ser un parámetro útil en la valoración de los pacientes pediátricos con obesidad. |
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ISSN: | 2387-0206 2387-0206 |
DOI: | 10.1016/j.medcle.2022.09.025 |