Treatment of acute high risk sub-massive pulmonary embolism with balloon angioplasty and thrombolysis simultaneously [version 2; peer review: 1 approved, 1 not approved]

• Published in: F1000 research Vol. 12; p. 1272
• Main Author: Arokiaraj, Mark Christopher
• Format: Journal Article
• Language: English
• Published: 2023
• Subjects: Acute submissive pulmonary embolism; Balloon angioplasty; Simultaneous thrombolysis; Maceration
• ISSN: 2046-1402; 2046-1402
• DOI: 10.12688/f1000research.137454.2

Background: Acute sub-massive pulmonary embolism is a common clinical condition, and it is associated with high mortality and morbidity. This condition is commonly associated with various co-morbidities and clinical circumstances. Methods: This is a case report series of 4 patients, wherein the thrombolysis and balloon angioplasty was performed simultaneously using a Cordis 6F diagnostic catheter and later exchanged with a 6F guide catheter in the respective pulmonary artery when a larger balloon was required. Results: All these four patients achieved successful revascularization of the respective pulmonary artery. One patient expired 30 hours after the procedure with a significant reduction in the symptoms suddenly, which was likely a second episode of pulmonary embolism. No bleeding manifestations were observed in any of the patients. The other three patients are on follow-up. Conclusion: Simultaneous coronary balloon dilatation and thrombolysis is a useful method in the treatment of high risk submassive acute pulmonary embolism. If needed, higher caliber balloons can be used for the same technique using guide catheters.