THU0110 Work Producivity in Rheumatoid Arthritis: Analysis from Multicenter Turkish Study

• Published in: Annals of the rheumatic diseases Vol. 74; no. Suppl 2; p. 233
• Main Authors: Pamuk, O.N., Cetin, P., Solmaz, D., Ertenli, I., Akar, S., Karaaslan, Y., Sari, R.A., Aksu, K., Atagunduz, P., Senturk, T., Cefle, A., Cobankara, V., Kobak, S., Koca, S.S., Pehlivan, Y., Tufan, A., Akyol, L., Gok, K., Kucuksahin, O., Donmez, S., Akkoc, N.
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.06.2015
• ISSN: 0003-4967; 1468-2060
• DOI: 10.1136/annrheumdis-2015-eular.5501

BackgroundRheumatoid arthritis (RA) is associated with a high disease burden and productivity loss due to joint damage and severe functional disability. There is only limited data on productivity loss in Turkish patients with RA.ObjectivesRA patients from 19 centers across Turkey underwent physical examination and completed questionnaires for global scales, HAQ-DI, EQ5D and WPS-RA. Student's t test and chi square analysis was used to compare variables. Factors associated with work productivity loss were analyzed by regression analysis.MethodsRA patients from 19 centers across Turkey underwent physical examination and completed questionnaires for global scales, HAQ-DI, EQ5D and WPS-RA. Student's t test and chi square analysis was used to compare variables. Factors associated with work productivity loss were analyzed by regression analysis.Results442 patients were enrolled (357 females, mean age: 51.7 years, mean disease duration 9.5 years). 91 patients (22.3%) were employed outside home. Non-working patients were older (44 vs 41, p<0.001), more likely to be female (87.1% vs 58.5%, p: <0.001). Of the remaining patients, 4.9% were unable to work due to arthritis.DMARD and biologic usage were similar in both groups (93.9% vs 95.9% and 37.4% vs 44.8%, respectively). Other features are summarized in Table below. Absenteeism and presenteeism were reported by the 23.7% and 37.6% of the patients, respectively. Higher swollen and tender joint counts,global scores and DAS28-ESR were associated with absenteeism in univariate analysis (p<0.01). Also biologic usage and lower HAQ score were related to less abstenteeism (p<0.05). In multivariate analysis, higher HAQ score (OR: 7.45, 95%CI: 1.26-44.1, p=0.027) was an independent factor for absenteeism. When assessing all RA patients, higher HAQ-DI score was associated with greater household activity impairment score in multivariate analysis (OR: 2.39, 95%CI: 1.77-3, p=0.001).Table 1.The general features and work productivity of patientsEmployedNot workingP(n=96)(n=343)Global VAS (0–100)35.7±26.235.4±25.6NSPain VAS (0–100)42.8±3242±31NSDAS28-ESR3.54+1.53.79±1.4NSRemission, (%)34.820.20.02HAQ-DI (0–3)1.34±0.71.47±0.680.03EQ-5D0.69±0.20.66±0.2NSDays of work missed2.07+5.3–Days with productivity at work reduced by ≥50%4.89+8.9–Rate of RA interference on work productivity3.3±5.9Days of household work missed3.7±7.25.7±9.20.03Rate of RA interference with household work productivity2.8±3.33.8±3.40.02ConclusionsRA has a major impact on productivity at home and at work. Higher disability score is an independent factor for both absenteeism and household activity impairment.AcknowledgementsThis study was supported by an unrestricted financial grant from UCB.Disclosure of InterestNone declared