H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

• Published in: Cell communication and signaling Vol. 9; no. 1; p. 25
• Main Authors: Müller, Anne, Oertli, Mathias, Arnold, Isabelle C
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.11.2011; BioMed Central; BMC
• Subjects: Adaptations; Autoimmune diseases; Bacteria; Cell interactions; Cellular signal transduction; Gastric cancer; Gastritis; Health aspects; Helicobacter pylori; immune evasion; Immune response; Immune system; Immunity; Immunological tolerance; Immunology; Immunomodulation; Inflammatory diseases; innate immune signaling; Lymphocytes T; Medical research; Pathogens; Pattern recognition; Persistent infection; Proteins; Review; Risk factors; Signal transduction; United Kingdom; Switzerland

Persistent infection with the gastric bacterial pathogen Helicobacter pylori causes gastritis and predisposes carriers to a high gastric cancer risk, but has also been linked to protection from allergic, chronic inflammatory and autoimmune diseases. In the course of tens of thousands of years of co-...