P192 Eus-guided through the needle microbiopsy; a useful adjunct in the investigation of pancreatic cystic lesions

• Published in: Gut Vol. 72; no. Suppl 2; pp. A152 - A153
• Main Authors: Ahmed, Wafaa, Mirzaali, Mikaeil, Everett, Simon, Paranandi, Bharat, Huggett, Matthew, On, Wei
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Society of Gastroenterology 18.06.2023; BMJ Publishing Group LTD
• Subjects: Biopsy; Complications; Diagnosis; Pancreas; Pancreatitis; Patients; Poster presentations; Surveillance
• ISSN: 0017-5749; 1468-3288
• DOI: 10.1136/gutjnl-2023-BSG.261

IntroductionEndoscopic ultrasound-guided through-the-needle microbiopsy (EUS-TTNB) forceps is a recent development that facilitates sampling of the walls of pancreatic cystic lesions (PCL) for histological analysis. We aimed to assess the impact of EUS-TTNB and its influence on patient management in a tertiary pancreas centre.MethodsA prospective database of consecutive patients who underwent EUS-TTNB from March 2020 to August 2022 was retrospectively analysed.ResultsThirty-four patients (22 female) were identified. Technical success was achieved in all cases. Adequate specimens for histological diagnosis were obtained in 25 (74%) cases. Overall, EUS-TTNB led to a change in management in 24 (71%) cases. Sixteen (47%) patients were downstaged, with 5 (15%) discharged from surveillance. Eight (24%) were upstaged, with 5 (15%) referred for surgical resection. In the 10 (29%) cases without change in management, 7 (21%) had confirmation of diagnosis with no change in surveillance, and 3 (9%) had insufficient biopsies on EUS-TTNB. Two (6%) patients developed post-procedural pancreatitis, and 1 (3%) developed peri-procedural intracystic bleeding with no subsequent clinical sequelae.ConclusionsEUS-TTNB permits histological confirmation of the nature of PCL, which can alter management outcomes. Care should be taken in patient selection and appropriately consented due to the adverse event rate.