Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity

Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β -L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of ( 3S , 4S, 5S, 6R...

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Published inBMC chemistry Vol. 5; no. 1; p. 7
Main Author Ghoneim, Amira Atef
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 11.02.2011
Springer Nature B.V
BioMed Central Ltd
BioMed Central
BMC
Subjects
Bacteria
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
E coli
Ethanol
Gram-positive bacteria
Mass spectrometry
Organic and Medicinal Chemistry
Research Article
Bacillus Cereus
Toluene Sulfonic Acid
Thioglycolic Acid
Sodium Bicarbonate Solution
Ammonium Thiocyanate
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Summary:Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β -L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of ( 3S , 4S, 5S, 6R ) 3, 4, 5-triacetoxy-2-methyl-7,9-diaza-1-oxa-spiro [4,5]decane-10-one-8-thione (7).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1752-153X
1752-153X
2661-801X
DOI:10.1186/1752-153X-5-7