Ondasetron versus haloperidol for the treatment of postcardiotomy delirium: a prospective, randomized, double-blinded study

• Published in: Journal of cardiothoracic surgery Vol. 7; no. 1; p. 25
• Main Authors: Tagarakis, Georgios I, Voucharas, Christos, Tsolaki, Fani, Daskalopoulos, Marios E, Papaliagkas, Vassilios, Parisis, Charalampos, Gogaki, Eleni, Tsagalas, Iotalias, Sataitidis, Iotalias, Tsolaki, Magda, Tsilimingas, Nikolaos B
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.03.2012; BioMed Central; BMC
• Subjects: Aged; Aged, 80 and over; Analysis of Variance; Cardiac Surgical Procedures - adverse effects; Comparative analysis; Delirium; Delirium - drug therapy; Delirium - etiology; Dosage and administration; Double-Blind Method; Drug therapy; Female; Haloperidol; Haloperidol - therapeutic use; Heart; Heart surgery; Hospitalization; Hospitals; Humans; Male; Neuropsychological Tests; Ondansetron; Ondansetron - therapeutic use; Postoperative Complications - drug therapy; Postoperative Complications - etiology; Prospective Studies; Risk factors; Schizophrenia; Statistical analysis; Stroke; Surgery; Thoracic surgery; Greece

To investigate the controlling efficacy of ondasetron and haloperidol in regard to the postcardiotomy delirium. We included in this prospective, randomized, double-blinded study 80 patients who developed delirium after heart surgery with the application of heart lung-machine. The patients were divid...