Automated diagnosis of diabetic retinopathy and glaucoma using fundus and OCT images

• Published in: Lipids in health and disease Vol. 11; no. 1; p. 73
• Main Authors: Pachiyappan, Arulmozhivarman, Das, Undurti N, Murthy, Tatavarti Vsp, Tatavarti, Rao
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.06.2012; BioMed Central; BMC
• Subjects: Algorithms; Aneurysm - diagnosis; Automation; Automation, Laboratory; Diabetes; Diabetic retinopathy; Diabetic Retinopathy - diagnosis; Diagnosis; Eyes & eyesight; Fundus image; Fundus Oculi; Glaucoma; Glaucoma - diagnosis; Humans; Image processing; Life sciences; Medical imaging; Medical imaging equipment; Noise; OCT; Optical tomography; Optics; Retina; Retinal Hemorrhage - diagnosis; Retinal Vessels - pathology; RNFL; Rural areas; Snakes; Studies; Tomography; Tomography, Optical Coherence
• ISSN: 1476-511X; 1476-511X
• DOI: 10.1186/1476-511X-11-73

We describe a system for the automated diagnosis of diabetic retinopathy and glaucoma using fundus and optical coherence tomography (OCT) images. Automatic screening will help the doctors to quickly identify the condition of the patient in a more accurate way. The macular abnormalities caused due to diabetic retinopathy can be detected by applying morphological operations, filters and thresholds on the fundus images of the patient. Early detection of glaucoma is done by estimating the Retinal Nerve Fiber Layer (RNFL) thickness from the OCT images of the patient. The RNFL thickness estimation involves the use of active contours based deformable snake algorithm for segmentation of the anterior and posterior boundaries of the retinal nerve fiber layer. The algorithm was tested on a set of 89 fundus images of which 85 were found to have at least mild retinopathy and OCT images of 31 patients out of which 13 were found to be glaucomatous. The accuracy for optical disk detection is found to be 97.75%. The proposed system therefore is accurate, reliable and robust and can be realized.