Nitric oxide and myocardial function in heart failure: friend or foe?

• Published in: Heart (British Cardiac Society) Vol. 88; no. 6; pp. 564 - 566
• Main Authors: Cotton, J M, Kearney, M T, Shah, A M
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Cardiovascular Society 01.12.2002; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; Copyright 2002 by Heart
• Subjects: Biological and medical sciences; Cardiology. Vascular system; DCM; dilated cardiomyopathy; endothelial NOS; Endothelium; eNOS; Heart; Heart failure; Heart Failure - etiology; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Heart muscle; Heart rate; Human subjects; Humans; inducible NOS; iNOS; Medical sciences; myocardial function; Myocardial Infarction - etiology; neuronal NOS; Nitric oxide; Nitric Oxide - physiology; nNOS; NO synthase; NOS; Physiological aspects; Physiology; Rodents; sarcoplasmic reticulum; Studies; Viewpoint; Workloads; United States; Human; Heart failure; Cardiac performance; Pathophysiology; Enzyme; Heart disease; Nitric oxide; Cardiovascular disease; Exploration; Oxidoreductases; Review; Nitric-oxide synthase

There is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac functionThere is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac func...