Nitric oxide and myocardial function in heart failure: friend or foe?

There is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac functionThere is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac func...

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Bibliographic Details
Published inHeart (British Cardiac Society) Vol. 88; no. 6; pp. 564 - 566
Main Authors Cotton, J M, Kearney, M T, Shah, A M
Format Journal Article
LanguageEnglish
Published London BMJ Publishing Group Ltd and British Cardiovascular Society 01.12.2002
BMJ
BMJ Publishing Group Ltd
BMJ Publishing Group LTD
Copyright 2002 by Heart
Subjects
Biological and medical sciences
Cardiology. Vascular system
DCM
dilated cardiomyopathy
endothelial NOS
Endothelium
eNOS
Heart
Heart failure
Heart Failure - etiology
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart muscle
Heart rate
Human subjects
Humans
inducible NOS
iNOS
Medical sciences
myocardial function
Myocardial Infarction - etiology
neuronal NOS
Nitric oxide
Nitric Oxide - physiology
nNOS
NO synthase
NOS
Physiological aspects
Physiology
Rodents
sarcoplasmic reticulum
Studies
Viewpoint
Workloads
United States
Human
Heart failure
Cardiac performance
Pathophysiology
Enzyme
Heart disease
Nitric oxide
Cardiovascular disease
Exploration
Oxidoreductases
Review
Nitric-oxide synthase
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Summary:There is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac functionThere is good evidence that nitric oxide has important autocrine/paracrine effects in the myocardium, serving to optimise and fine tune cardiac function
Bibliography:istex:25DE61F1B8D4561AA328932D6E5464C11389DADF
Correspondence to:
 Professor Ajay M Shah, Department of Cardiology, Guy’s King’s & St Thomas’s School of Medicine, Bessemer Road, London SE5 9PJ, UK;
 ajay.shah@kcl.ac.uk
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PMID:12433878
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Correspondence to: …Professor Ajay M Shah, Department of Cardiology, Guy’s King’s & St Thomas’s School of Medicine, Bessemer Road, London SE5 9PJ, UK; …ajay.shah@kcl.ac.uk
ISSN:1355-6037
1468-201X
1468-201X
DOI:10.1136/heart.88.6.564