The Comparison of Two Single-cell Sequencing Platforms: BD Rhapsody and 10x Genomics Chromium

• Published in: Current genomics Vol. 21; no. 8; pp. 602 - 609
• Main Authors: Gao, Caixia, Zhang, Mingnan, Chen, Lei
• Format: Journal Article
• Language: English
• Published: United Arab Emirates Bentham Science Publishers Ltd 01.12.2020; Benham Science Publishers; Bentham Science Publishers
• Subjects: Chromium; Gene expression; Gene sequencing; Genomics; Medical research; Platforms; Transcription; Single-cell sequencing; 10x genomics chromium; transcriptome sequencing; technology comparison; DNA; BD rhapsody

The cell is the unit of life for all organisms, and all cells are certainly not the same. So the technology to generate transcription expression or genomic DNA profiles from single cells is crucial. Since its establishment in 2009, single-cell RNA sequencing (scRNA-seq) has emerged as a major driver...