A “natural experiment” in cardiovascular epidemiology in the early 21st century

• Published in: Heart (British Cardiac Society) Vol. 89; no. 3; pp. 255 - 257
• Main Authors: Sekikawa, A, Horiuchi, B Y, Edmundowicz, D, Ueshima, H, Curb, J D, Sutton-Tyrrell, K, Okamura, T, Kadowaki, T, Kashiwagi, A, Mitsunami, K, Murata, K, Nakamura, Y, Rodriguez, B L, Kuller, L H
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Cardiovascular Society 01.03.2003; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; Copyright 2003 by Heart
• Subjects: Analysis; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Cardiovascular disease; Cardiovascular research; Clinical manifestations. Epidemiology. Investigative techniques. Etiology; Cohort Studies; Coronary Disease - mortality; Coronary heart disease; Developed Countries; Developing Countries; Emigration and Immigration; Epidemiology; Health risk assessment; Humans; Japan; Japan - ethnology; Japanese Americans; Medical sciences; Mortality; Patient outcomes; Risk Factors; Studies; United States; United States - epidemiology; Viewpoint; World; United States; Japan; Hawaii; Human; Hypertension; Urine; Excretion; Cardiovascular disease; Coronary heart disease; Sodium; Cohort study; Risk factor; Blood pressure; Potassium; Comparative study; Bibliographic review
• ISSN: 1355-6037; 1468-201X
• DOI: 10.1136/heart.89.3.255

Despite similar traditional risk factors, morbidity and mortality rates from coronary heart disease in western and non-western cohorts remain substantially different. Careful study of such cohorts may help identify novel risk factors for CHD, and contribute to the formulation of new preventive strategies