A case of corneal keloid: clinical, surgical, pathological, and ultrastructural characteristics

• Published in: British journal of ophthalmology Vol. 78; no. 7; pp. 568 - 571
• Main Authors: Risco, J M, Huaman, A, Antonios, S R
• Format: Journal Article
• Language: English
• Published: BMA House, Tavistock Square, London, WC1H 9JR BMJ Publishing Group Ltd 01.07.1994; BMJ; BMJ Publishing Group LTD
• Subjects: Aged; Biological and medical sciences; Corneal Diseases - pathology; Corneal Diseases - surgery; Humans; Injuries of the orbit. Foreign bodies of the eye. Diseases due to physical agents; Keloid - pathology; Keloid - surgery; Male; Medical sciences; Microscopy, Electron; Traumas. Diseases due to physical agents; Case study; Human; Pathology; Eye disease; Cornea; Histopathology; Treatment; Cheloid; Surgery; Exploration; Keratopathy; Trauma
• ISSN: 0007-1161; 1468-2079
• DOI: 10.1136/bjo.78.7.568

A 69-year-old patient developed a localised, whitish, elevated, corneal lesion with a smooth and glistening surface following trauma, without evidence of corneal perforation. Twelve months later, the lesion showed evidence of slow growth. An excisional biopsy was then performed. Histopathologically, the lesion was covered by non-keratinised squamous epithelium and was comprised of randomly oriented collagen fibres containing active fibroblasts. Blood vessels were noted deep in the lesion. Ultrastructurally, the cell population was formed by fibroblasts and myofibroblasts, similar to keloids of the skin. The clinical, pathological, and ultrastructural features of the corneal lesion are compatible with a corneal keloid.