Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation?

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Bibliographic Details
Published inAnnals of the rheumatic diseases Vol. 78; no. 8; pp. 1015 - 1018
Main Authors Siebert, Stefan, Millar, Neal L, McInnes, Iain B
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and European League Against Rheumatism 01.08.2019
BMJ Publishing Group LTD
BMJ Publishing Group
Subjects
Arthritis
Arthritis, Psoriatic
Autoimmune diseases
Clinical trials
Cytokines
Disease
DMARDs (biologic)
Editorial
Genomics
Helper cells
Humans
Inflammation
Inflammatory bowel disease
Interleukin 12
Interleukin 23
Interleukin 27
Interleukin-17
Interleukin-23 Subunit p19
Keratinocytes
Lymphocytes
Lymphocytes T
Mucosa
Pathogenesis
Polyclonal antibodies
Psoriasis
Roles
spondyloarthritis
Stat3 protein
Studies
Synovial Membrane
Tumor necrosis factor-TNF
Wound healing
Zinc finger proteins
DMARDs (biologic)
spondyloarthritis
cytokines
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Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0003-4967
1468-2060
DOI:10.1136/annrheumdis-2018-213654