Correlation between interleukin 10 gene promoter region polymorphisms and clinical manifestations in Japanese patients with Sjögren’s syndrome

[...]IL10 gene promoter region polymorphism affected the age at onset of SS, and supported evidence that variation in the age at onset of SS was genetically determined.

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Bibliographic Details
Published inAnnals of the rheumatic diseases Vol. 62; no. 11; pp. 1117 - 1118
Main Authors Origuchi, T, Kawasaki, E, Ide, A, Kamachi, M, Tanaka, F, Ida, H, Kawakami, A, Migita, K, Eguchi, K
Format Journal Article
LanguageEnglish
Published England BMJ Publishing Group Ltd and European League Against Rheumatism 01.11.2003
BMJ Publishing Group Ltd
BMJ Publishing Group LTD
Subjects
Age
Age of Onset
Analysis
Autoimmune diseases
Care and treatment
Case-Control Studies
Cytokines
DNA polymorphism
Exocrine glands
Genes
Genetic aspects
Genetic Predisposition to Disease
Genotype
Haplotypes
Health aspects
Histocompatibility
Humans
Interleukin-10
Interleukin-10 - genetics
Japan
Letter
Lymphocytes
Medical research
Medicine, Experimental
Patients
Physiological aspects
Polymorphism, Genetic
Prevention
Promoter Regions, Genetic
Rheumatic diseases
Sjogren's syndrome
Sjogren's Syndrome - genetics
Sjogren's Syndrome - immunology
Sjögren’s syndrome
Japan
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Summary:[...]IL10 gene promoter region polymorphism affected the age at onset of SS, and supported evidence that variation in the age at onset of SS was genetically determined.
Bibliography:Correspondence to:
 Tomoki Origuchi, Nagasaki University School of Health Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8520, Japan; 
 origuchi@net.nagasaki-u.ac.jp
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PMID:14583579
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href:annrheumdis-62-1117.pdf
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ISSN:0003-4967
1468-2060
DOI:10.1136/ard.62.11.1117