Ultrasonographically detected gallbladder polyps: a reason for concern? A seven-year follow-up study

• Published in: BMC gastroenterology Vol. 8; no. 1; p. 41
• Main Authors: Kratzer, Wolfgang, Haenle, Mark M, Voegtle, Andrea, Mason, Richard A, Akinli, Atilla S, Hirschbuehl, Klaus, Schuler, Andreas, Kaechele, Volker
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.09.2008; BioMed Central; BMC
• Subjects: Adolescent; Adult; Aged; Care and treatment; Chile; Data Collection; Diagnosis; Disease Progression; Female; Follow-Up Studies; Gallbladder cancer; Gallbladder Diseases - diagnostic imaging; Gallbladder Diseases - epidemiology; Gallbladder Diseases - pathology; Germany; Health aspects; Humans; Incidental Findings; Japan; Longitudinal Studies; Male; Methods; Middle Aged; New Zealand; Polyps - diagnostic imaging; Polyps - epidemiology; Polyps - pathology; Prevalence; Prospective Studies; Ultrasonography; Ultrasound imaging; United States; Germany
• ISSN: 1471-230X; 1471-230X
• DOI: 10.1186/1471-230X-8-41

The management of coincidental detected gallbladder polyps (GP) is still nebulous. There are few published data regarding their long-term growth. Objective of the present study was to investigate the prevalence and growth of gallbladder polyps in a survey of unselected subjects from the general population of a complete rural community. A total of 2,415 subjects (1,261 women; 1,154 men) underwent ultrasound examination of the gallbladder, in November 1996 as part of a prospective study. Subjects in whom GP were detected at the initial survey underwent follow-up ultrasound examinations after 30 and 84 months. At the initial survey gallbladder polyps were detected in 34 subjects (1.4%; females: 1.1%, range 14 to 74 years; males: 1.7%, range 19 to 63 years). Median diameter was 5 +/- 2.1 mm (range 2 to 10 mm) at the initial survey, 5 mm +/- 2.8 mm (range 2 to 12 mm) at 30 months and 4 +/- 2.3 mm (range 2 to 9 mm) at 84 months. At the time of first follow-up no change in diameter was found in 81.0% (n = 17), reduction in diameter in 4.8% (n = 1) and increase in diameter in 14.3% (n = 3). At the time of second follow-up no increase in polyp diameter was found in 76.9% (n = 10) and reduction in diameter in 7.7% (n = 1). No evidence of malignant disease of the gallbladder was found. Over a period of seven years little change was measured in the diameter of gallbladder polyps. There was no evidence of malignant disease of the gallbladder in any subject.