Trials and fast changing technologies: the case for tracker studies

Evaluating treatments is difficult when developments or variants arise frequently. In these circumstances randomized controlled trials should not await stability, but should track progress over time, providing unbiased comparisons at each stage.

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Bibliographic Details
Published inBMJ Vol. 320; no. 7226; pp. 43 - 46
Main Authors Lilford, Richard J, Braunholtz, David A, Greenhalgh, Roger, Edwards, Sarah J L
Format Journal Article
LanguageEnglish
Published London British Medical Journal Publishing Group 01.01.2000
British Medical Association
BMJ Publishing Group LTD
BMJ Publishing Group
British Medical Journal
EditionInternational edition
Subjects
Biological and medical sciences
Clinical trial. Drug monitoring
Clinical trials
Data Collection
Education and Debate
Emerging technology
Ethics committees
Evaluation Studies as Topic
Evidence-Based Medicine
Experimentation
General pharmacology
Health outcomes
Medical research
Medical sciences
Medical technology
Pharmacology. Drug treatments
Randomized Controlled Trials as Topic - methods
Randomized Controlled Trials as Topic - trends
Research methods
Sample Size
Surgeons
Technology
Technology assessment
Human
Evaluation
Randomization
Performance requirement
Technology
Scientific research
Tracking(movable target)
Clinical trial
Pharmacology
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Summary:Evaluating treatments is difficult when developments or variants arise frequently. In these circumstances randomized controlled trials should not await stability, but should track progress over time, providing unbiased comparisons at each stage.
Bibliography:href:bmj-320-43.pdf
Correspondence to: D A Braunholtz
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PMID:10617532
ArticleID:bmj.320.7226.43
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ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Correspondence to: D A Braunholtz D.A.Braunholtz@Bham.ac.uk
ISSN:0959-8138
0959-8146
1468-5833
1756-1833
DOI:10.1136/bmj.320.7226.43